LOCUS       scaffold_812            6269 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  .
ACCESSION   scaffold_812
VERSION     scaffold_812
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0
            Run date     :: 2025-03-18 15:13:47
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6269
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6269
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[12:5952]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="30000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      13..5952
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="30000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6269
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6269
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             13..5952
                     /NRPS_PKS="Domain: PCP (219-289). E-value: 1.2e-15. Score:
                     49.3. Matches aSDomain: nrpspksdomains_18247_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (309-589). E-value:
                     3.2e-43. Score: 139.7. Matches aSDomain:
                     nrpspksdomains_18247_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (767-1176). E-value:
                     4.3e-103. Score: 336.9. Matches aSDomain:
                     nrpspksdomains_18247_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1283-1353). E-value: 2.6e-16.
                     Score: 51.5. Matches aSDomain: nrpspksdomains_18247_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1398-1654). E-value:
                     9.8e-47. Score: 151.2. Matches aSDomain:
                     nrpspksdomains_18247_Condensation_LCL.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     280.3; E-value: 4.1e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="18247"
                     /sec_met_domain="Condensation (E-value: 9e-43, bitscore:
                     132.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-107, bitscore:
                     345.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.6e-15, bitscore:
                     41.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="CAVDCTFKEINEVEEPKITIGKPLCNCKLYILDKNLNVVPIGVEG
                     EIFIGGYGVGKGYLNRPELTKEKFVECPFHDGNPHDLIMYRTGDLGKWMENGEIDYLGR
                     IDFQVKIHGQRIELSEIENTIKEIEGIEYCAVIDKIKESGDKYLVCYYISGKGISGRDI
                     RNYLKSKLPLYMVPNYFISIENIPVTSNGKLNRKALPEPNISDVITEQYIVPETEIEKM
                     VCKIYSSVFNIDENEIGKMSDFHELGGDSLNAIRMTSKIEKELNIKINIKDILSNSSVF
                     ELSKFIENNINNENGIHESEIIKRYNSKEFPITSQQLGVYIDSIKNSNSIMYNVPYCYK
                     LKENVNIEKIKKALLNIFNEQEILRSKYYDKEINDKTEVYGFIDDECSLEFEEYTHENA
                     NSFIRPFELSKAPLIRVGFINNEALLIDMHHIISDGMTMSNISKYLNNYYHDLSNEKLE
                     IQFSDYAINLNEKMNESYFNKQIEFYKQMFDDEEYEELNIQGIKKSLKKNENELKIKSC
                     TMEITENNSSLINKFIENNGLSKTSFFLSIYGFVLSKYSGQNIIYSSIVNANRNNRYTE
                     NMIGMFVSTQPILLKYKNEETPFIDIMKQTMNNLIDLYDNLDISFSSLKNTLKLKNVNN
                     IFIYQPKSIIESNVNDSIFAENEDNDVFTNDDGTYNNNDDNINNISKFDLSISIIEKEN
                     KYIISVDFNPNIYEEKLINNIVKSYIEVVNNVNHYHEKIKDIEYIPREMKEKILNVFNN
                     NNCEYEHNKLYHVEFSRIAKENASKTAIINNDEKISFKKLDEMSNSLAHYLRSQGIKRN
                     DIVPIVSERSYYYVVACIAIMKAGGAYLPIDPEFPIDRIEYMISETNAKFILSYITSEK
                     NNQKLQFENISTYPLDRHNYQHNIQEITNVNDSSDLSYVIFTSGTTGKPKGTLITHDNL
                     INYCMYCQTYNGKEDVYGDDYDNVLAFSKFTFDMSVTEISYPLLRGSTVILCNDSEFND
                     SELLSYLIKKHHVMNMFTAPSRFKNYLTNDNFAKAVTNLKWVIFGGEQLDYNNVKYLQH
                     NTNARIYNGYGPTEATACCTYKEIHRNNEDKMNSNIGKPLCNCNIYILDKNMKPVPIGI
                     EGEIFIGGYGVCKGYLNREELTHEKFVDCPFFKINNSPSKMYRTGDLGKWTEDGDIAYL
                     GRIDFQVKIRGQRIELSEITNTIIEMNGINNAVVIDKQNENGNKYLVCYYMTNENINGK
                     EINDYLKAKLPLYMIPSYFIKIERVPVTPNGKLDRNALPEPQKSDLITEQYVAPETEIE
                     KLICRIYSKLFNIDEKEIGKMSDFYALGGDSLNAIRVISEIKKNLNIKLNIKDIMNNST
                     VLSLASLIESIKSSNDNNYETGRINSYHKMEYPITPLLSGLAINANGFDLESFKNSTDN
                     MNIYYQLKEPISIEKLTKAFNLIINRHKVLKTVFIEKNVNGKNKIYGKIRDNVKLEIEH
                     YTVENFESFKRPFDITKDLLIRVGIIDNSVLMIDIDHKISDGYSFGILMKELYQIYNDE
                     ILDELPIQYSDYAIQYDEKVSSKTFSHQLEYYKSVFDENVNTVQLPTKKNINENNIQKE
                     YKMKIVNTEPEIYNIVNKISKENNISKTAFFLTLYSFVLSQYSGQNNIFSAIMSSNRTN
                     DNTENLIGLFVRYMPVLVKIENTNLIDLMKKCMDMILTIYGFDIPFSKLSEELHLPQSN
                     SWFKFDPYEMVNNDELNFVKLINHDDIYKLFNKENPSVKNDIPFSSESADLQFVVTEKI
                     NYYEINFIYNSAIYEESLINDMINHFINIIKNENYFKNNTDEILINNSSSIDISESDSV
                     YVSEKSVESSKKSNIILIDENKITKRRIFRRRIRRRRRNHQDIKKSSFVDLSSSYSTLY
                     ESSQNSLTEESLVINTTIKEGKKKRFYHRIFTNDSTWVNSSTSEMSRSESERNDSSLIL
                     ESEIENKKKTNKKLHKFGKKIKKYINKLKINKKQERIIVIDEELKI"
     CDS_motif       130..219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0001"
                     /evalue="2.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="18247"
                     /protein_end="69"
                     /protein_start="39"
                     /score="45.7"
                     /tool="antismash"
                     /translation="PIGVEGEIFIGGYGVGKGYLNRPELTKEKF"
     CDS_motif       313..378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0002"
                     /evalue="4.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="18247"
                     /protein_end="122"
                     /protein_start="100"
                     /score="34.7"
                     /tool="antismash"
                     /translation="YLGRIDFQVKIHGQRIELSEIE"
     aSDomain        670..879
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_18247_PCP.1"
                     /evalue="1.20E-15"
                     /label="18247_PCP.1"
                     /locus_tag="18247"
                     /protein_end="289"
                     /protein_start="219"
                     /score="49.3"
                     /tool="antismash"
                     /translation="EKMVCKIYSSVFNIDENEIGKMSDFHELGGDSLNAIRMTSKIEKE
                     LNIKINIKDILSNSSVFELSKFIEN"
     aSDomain        940..1779
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_18247_Condensation_LCL.1"
                     /evalue="3.20E-43"
                     /label="18247_Condensation_LCL.1"
                     /locus_tag="18247"
                     /protein_end="589"
                     /protein_start="309"
                     /score="139.7"
                     /tool="antismash"
                     /translation="EFPITSQQLGVYIDSIKNSNSIMYNVPYCYKLKENVNIEKIKKAL
                     LNIFNEQEILRSKYYDKEINDKTEVYGFIDDECSLEFEEYTHENANSFIRPFELSKAPL
                     IRVGFINNEALLIDMHHIISDGMTMSNISKYLNNYYHDLSNEKLEIQFSDYAINLNEKM
                     NESYFNKQIEFYKQMFDDEEYEELNIQGIKKSLKKNENELKIKSCTMEITENNSSLINK
                     FIENNGLSKTSFFLSIYGFVLSKYSGQNIIYSSIVNANRNNRYTENMIGMFVSTQPIL"
     aSModule        940..4071
                     /complete
                     /domains="nrpspksdomains_18247_Condensation_LCL.1"
                     /domains="nrpspksdomains_18247_AMP-binding.1"
                     /domains="nrpspksdomains_18247_PCP.2"
                     /locus_tags="18247"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1006..1110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0003"
                     /evalue="5.30E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="18247"
                     /protein_end="366"
                     /protein_start="331"
                     /score="12.4"
                     /tool="antismash"
                     /translation="MYNVPYCYKLKENVNIEKIKKALLNIFNEQEILRS"
     CDS_motif       1297..1347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0004"
                     /evalue="1.40E-03"
                     /label="C3_starter_134-155"
                     /locus_tag="18247"
                     /protein_end="445"
                     /protein_start="428"
                     /score="11.7"
                     /tool="antismash"
                     /translation="HHIISDGMTMSNISKYL"
     CDS_motif       1708..1776
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0005"
                     /evalue="2.00E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="18247"
                     /protein_end="588"
                     /protein_start="565"
                     /score="20.3"
                     /tool="antismash"
                     /translation="VNANRNNRYTENMIGMFVSTQPI"
     aSDomain        2314..3540
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_18247_AMP-binding.1"
                     /evalue="4.30E-103"
                     /label="18247_AMP-binding.1"
                     /locus_tag="18247"
                     /protein_end="1176"
                     /protein_start="767"
                     /score="336.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FSRIAKENASKTAIINNDEKISFKKLDEMSNSLAHYLRSQGIKRN
                     DIVPIVSERSYYYVVACIAIMKAGGAYLPIDPEFPIDRIEYMISETNAKFILSYITSEK
                     NNQKLQFENISTYPLDRHNYQHNIQEITNVNDSSDLSYVIFTSGTTGKPKGTLITHDNL
                     INYCMYCQTYNGKEDVYGDDYDNVLAFSKFTFDMSVTEISYPLLRGSTVILCNDSEFND
                     SELLSYLIKKHHVMNMFTAPSRFKNYLTNDNFAKAVTNLKWVIFGGEQLDYNNVKYLQH
                     NTNARIYNGYGPTEATACCTYKEIHRNNEDKMNSNIGKPLCNCNIYILDKNMKPVPIGI
                     EGEIFIGGYGVCKGYLNREELTHEKFVDCPFFKINNSPSKMYRTGDLGKWTEDGDIAYL
                     GRIDFQVKIR"
     CDS_motif       2503..2541
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0006"
                     /evalue="5.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="18247"
                     /protein_end="843"
                     /protein_start="830"
                     /score="16.5"
                     /tool="antismash"
                     /translation="AIMKAGGAYLPID"
     CDS_motif       2734..2793
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0007"
                     /evalue="7.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="18247"
                     /protein_end="927"
                     /protein_start="907"
                     /score="27.8"
                     /tool="antismash"
                     /translation="SYVIFTSGTTGKPKGTLITH"
     CDS_motif       3322..3411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0008"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="18247"
                     /protein_end="1133"
                     /protein_start="1103"
                     /score="36.7"
                     /tool="antismash"
                     /translation="PIGIEGEIFIGGYGVCKGYLNREELTHEKF"
     CDS_motif       3505..3567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0009"
                     /evalue="6.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="18247"
                     /protein_end="1185"
                     /protein_start="1164"
                     /score="34.3"
                     /tool="antismash"
                     /translation="YLGRIDFQVKIRGQRIELSEI"
     aSDomain        3862..4071
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_18247_PCP.2"
                     /evalue="2.60E-16"
                     /label="18247_PCP.2"
                     /locus_tag="18247"
                     /protein_end="1353"
                     /protein_start="1283"
                     /score="51.5"
                     /tool="antismash"
                     /translation="EKLICRIYSKLFNIDEKEIGKMSDFYALGGDSLNAIRVISEIKKN
                     LNIKLNIKDIMNNSTVLSLASLIES"
     aSDomain        4207..4974
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_18247_Condensation_LCL.2"
                     /evalue="9.80E-47"
                     /label="18247_Condensation_LCL.2"
                     /locus_tag="18247"
                     /protein_end="1654"
                     /protein_start="1398"
                     /score="151.2"
                     /tool="antismash"
                     /translation="STDNMNIYYQLKEPISIEKLTKAFNLIINRHKVLKTVFIEKNVNG
                     KNKIYGKIRDNVKLEIEHYTVENFESFKRPFDITKDLLIRVGIIDNSVLMIDIDHKISD
                     GYSFGILMKELYQIYNDEILDELPIQYSDYAIQYDEKVSSKTFSHQLEYYKSVFDENVN
                     TVQLPTKKNINENNIQKEYKMKIVNTEPEIYNIVNKISKENNISKTAFFLTLYSFVLSQ
                     YSGQNNIFSAIMSSNRTNDNTENLIGLFVRYMPV"
     CDS_motif       4225..4323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0010"
                     /evalue="1.30E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="18247"
                     /protein_end="1437"
                     /protein_start="1404"
                     /score="17.5"
                     /tool="antismash"
                     /translation="IYYQLKEPISIEKLTKAFNLIINRHKVLKTVFI"
     CDS_motif       4510..4563
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0011"
                     /evalue="1.10E-05"
                     /label="C3_DCL_135-156"
                     /locus_tag="18247"
                     /protein_end="1517"
                     /protein_start="1499"
                     /score="18.0"
                     /tool="antismash"
                     /translation="ISDGYSFGILMKELYQIY"
     CDS_motif       4912..4959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_18247_0012"
                     /evalue="1.70E-03"
                     /label="C5_LCL_267-296"
                     /locus_tag="18247"
                     /protein_end="1649"
                     /protein_start="1633"
                     /score="10.9"
                     /tool="antismash"
                     /translation="SNRTNDNTENLIGLFV"
ORIGIN
        1 ggacctacag aatgtgccgt tgattgtacg tttaaagaaa taaatgaagt tgaagaacca
       61 aagatcacaa ttggtaaacc actttgtaat tgtaaacttt atattttaga taagaatttg
      121 aatgtggtac caattggagt tgaaggagaa atctttattg gaggatatgg agttggtaaa
      181 ggatatttaa accgaccaga attaactaaa gaaaagtttg ttgaatgtcc attccatgat
      241 ggaaatccac atgatttaat tatgtatcga acgggagatc ttggtaaatg gatggaaaat
      301 ggagaaattg attatttagg aagaattgat ttccaagtta aaattcatgg acaaagaatt
      361 gaattaagtg aaattgaaaa tacgattaaa gaaatcgaag gaattgaata ttgtgcagtc
      421 attgataaaa ttaaagaatc cggagataaa tatttagtat gttattacat tagtggaaaa
      481 ggaatttcag gaagagatat tcgtaattat ttgaagagta aacttccatt atatatggtt
      541 ccaaattact ttatttcgat tgaaaatatt ccagtcacca gtaatggtaa attgaataga
      601 aaagcattac cagaaccaaa tatttcagat gtcattactg aacaatatat tgtaccagaa
      661 acggaaattg aaaagatggt atgtaaaatc tatagttcag tatttaatat cgatgagaat
      721 gaaattggta aaatgagtga tttccatgaa ttaggaggag atagtttgaa tgctatcaga
      781 atgacatcta aaattgaaaa agaattaaat attaaaatta atattaaaga tattctttct
      841 aattcaagtg tatttgaatt aagtaaattc attgaaaata acattaataa tgaaaatgga
      901 attcatgaat ccgaaattat taaaagatat aatagtaaag aattcccaat tacatcacaa
      961 caattaggtg tatatattga ttctattaaa aactcaaata gtatcatgta taatgttcca
     1021 tattgctata aattgaaaga aaacgttaat attgaaaaaa ttaagaaagc cttgcttaat
     1081 attttcaatg aacaagaaat attaagaagt aaatattatg ataaagaaat caatgataaa
     1141 accgaagtat atggtttcat tgatgatgaa tgttcacttg aatttgaaga atatacacat
     1201 gaaaacgcta attcatttat tagaccattt gaattatcaa aggcaccatt aataagagta
     1261 ggtttcatta ataatgaagc tttattgatt gatatgcatc atattatttc tgacggtatg
     1321 acaatgtcaa atatttccaa atatcttaat aattattacc atgacctttc taatgaaaaa
     1381 ttagaaattc aatttagtga ctatgcaatt aatttaaatg aaaagatgaa tgaatcatat
     1441 ttcaataaac aaattgaatt ctataaacaa atgtttgatg atgaagaata tgaagaattg
     1501 aatattcagg gtatcaaaaa atcgttaaag aaaaatgaaa atgaattaaa aataaaaagt
     1561 tgtacaatgg aaattactga aaacaacagt agtttaataa ataaattcat tgaaaataac
     1621 ggactcagta agacttcatt cttcctcagt atttatggtt ttgtcttatc taaatatagt
     1681 ggacaaaaca ttatttatag ttcaattgtt aatgctaata gaaataatag atacaccgaa
     1741 aacatgattg gtatgtttgt tagtacccaa ccaatattac ttaagtacaa gaatgaagaa
     1801 acaccattca ttgatatcat gaagcaaaca atgaataatt taattgattt atatgataat
     1861 ctcgatattt cattctcatc cttaaagaat accttaaaat taaagaatgt aaataatatc
     1921 tttatttatc aacctaaatc tattattgaa agtaatgtaa acgacagtat attcgcagaa
     1981 aatgaagata atgatgtatt cacaaatgat gatggaacct acaataataa tgatgataat
     2041 attaataata tttctaaatt tgatttatcc attagtatta tcgaaaaaga aaataaatat
     2101 ataatttcag tagattttaa tccaaatatc tatgaagaaa aattaattaa caacatcgtt
     2161 aaaagttaca ttgaggttgt taataacgtc aatcattatc atgaaaaaat aaaagatatt
     2221 gaatacattc caagagaaat gaaagaaaag atcttgaatg tatttaataa taataattgt
     2281 gaatatgaac acaataaatt atatcatgtt gaatttagta gaattgctaa ggaaaacgcc
     2341 agtaaaaccg ctattataaa taatgatgaa aagatttcat ttaagaagtt ggatgaaatg
     2401 agtaactctt tagcccatta cttaagaagc caaggtatta aaagaaatga tattgttcca
     2461 attgtaagtg aacgttcata ttactatgta gttgcttgca tagctattat gaaagcagga
     2521 ggagcttatt taccaattga tccagaattc ccaatcgatc gtattgaata catgatttcc
     2581 gaaacaaatg ctaaatttat tttgagttac attaccagtg aaaagaataa ccaaaaatta
     2641 caatttgaaa atatcagtac atatccatta gatagacata actatcaaca taacattcaa
     2701 gaaattacta atgttaatga tagtagtgat ctatcttacg ttatatttac ctcaggtact
     2761 accggtaaac caaaaggaac attaattaca catgataatt taattaacta ttgtatgtac
     2821 tgtcaaacct ataatggaaa ggaagatgta tatggagatg attatgataa tgtattagcc
     2881 ttctctaaat tcacctttga tatgtccgtt acggaaatta gttatccatt acttagaggt
     2941 tctacggtta ttttatgtaa cgactctgaa tttaatgatt ctgaattatt aagttacttg
     3001 attaagaaac atcatgtaat gaatatgttt acagctcctt ccagattcaa aaactattta
     3061 acaaatgata atttcgctaa agctgttacc aatctcaaat gggtcatctt tggaggtgaa
     3121 caacttgact ataataatgt aaaatatctt caacacaata ctaatgccag aatttacaat
     3181 ggatatggac caaccgaagc taccgcttgt tgtacctata aagaaattca tagaaataat
     3241 gaagataaga tgaattctaa tattggtaaa ccattatgta attgtaatat atacatttta
     3301 gataaaaata tgaaaccagt tcctattgga attgaaggag aaatcttcat tggtggttat
     3361 ggtgtttgta aaggatacct taatcgtgaa gaattaaccc atgaaaaatt cgttgattgt
     3421 ccattcttca agataaacaa ttcaccatcc aagatgtacc gtacaggaga cttaggtaaa
     3481 tggactgaag atggagatat tgcttattta ggaagaattg atttccaagt caagattcgt
     3541 ggacaaagaa ttgaattaag tgaaattact aatactatta ttgaaatgaa tggtattaat
     3601 aatgcagtcg ttatcgacaa acaaaacgaa aatggtaata aatatttagt atgttactac
     3661 atgacaaatg aaaatattaa tggaaaggaa attaatgatt atttaaaggc caagcttcca
     3721 ttatatatga ttccaagtta ctttatcaag attgaacgtg ttccagtgac accaaatggt
     3781 aaattagata gaaatgcatt accagaaccc caaaagtccg atttaattac ggaacaatat
     3841 gttgctccag aaaccgaaat cgaaaaatta atttgtagaa tttacagtaa attatttaat
     3901 attgatgaaa aagaaattgg taaaatgagt gacttttatg ccttaggtgg tgacagtttg
     3961 aacgctatta gagttatatc ggaaattaaa aagaatttga atattaaatt aaatataaag
     4021 gatattatga ataattcgac tgtactttca ttggcttctc taattgaatc tataaagtca
     4081 agcaatgata ataattatga aacaggaaga attaatagtt atcataagat ggaatatcca
     4141 attactccgt tactctctgg tttggccatc aatgccaacg gttttgatct tgaatcattt
     4201 aaaaattcca ccgataatat gaatatatat tatcaattga aggaacccat tagtatcgaa
     4261 aaattaacaa aggccttcaa cctaattatt aacagacata aagtcttaaa aaccgttttc
     4321 attgaaaaga atgtcaatgg taaaaataaa atatatggta agatacgtga taatgttaaa
     4381 ttagaaattg aacattacac cgtagaaaac tttgaaagct tcaaaagacc atttgatatt
     4441 acaaaagatt tattaataag agttggaata atagacaatt ccgtattaat gatcgatatt
     4501 gatcataaaa ttagtgatgg ttattccttt ggtattttga tgaaggaatt atatcaaatc
     4561 tataatgatg aaattttgga tgaattacca attcaatata gtgattatgc cattcaatat
     4621 gatgaaaagg tcagtagtaa gacattctct caccaacttg aatactataa atctgtattt
     4681 gacgaaaacg ttaatacggt tcaactacca actaaaaaga atataaatga aaataacatc
     4741 caaaaagaat ataagatgaa gattgttaat acagaaccgg aaatatacaa tatagttaat
     4801 aaaatatcaa aagaaaataa tatttccaaa accgctttct tccttactct ttacagtttt
     4861 gtcttgtctc agtattccgg acaaaataat atattctcag ctatcatgag ttctaataga
     4921 actaatgata acactgaaaa tcttatcggt ctctttgtta gatatatgcc agttttggtt
     4981 aaaattgaaa atactaattt gattgattta atgaaaaaat gtatggatat gattcttact
     5041 atttatggtt tcgatattcc attcagtaaa ctttctgaag aattacatct tccacaatca
     5101 aattcctggt ttaaatttga tccatacgaa atggtaaaca atgatgaatt aaactttgta
     5161 aagttaatta atcatgatga tatttataaa ttatttaata aagaaaatcc ttcggttaaa
     5221 aatgacattc catttagtag tgaatctgct gatcttcaat ttgtcgtaac ggaaaaaata
     5281 aattattatg aaattaactt tatatataat agtgctattt atgaagaaag cttaattaat
     5341 gacatgatta atcatttcat taatatcatt aaaaatgaaa attatttcaa aaataatact
     5401 gatgaaatat taataaataa tagttcatca attgatatct ccgaatcaga ttcagtttat
     5461 gtttctgaaa aatctgttga aagcagtaaa aaatcaaata taatattaat agacgaaaac
     5521 aagattacca agagaagaat atttagaaga agaataagga gaagaagaag aaatcatcaa
     5581 gatataaaga aatcctcatt tgttgatctc tctagtagtt acagtacatt atatgaaagt
     5641 agtcaaaaca gtttaactga agaaagttta gttataaata cgactattaa agagggtaaa
     5701 aagaaaagat tctatcatag aatatttaca aatgacagta cctgggttaa ttccagtact
     5761 tccgaaatga gtagatctga atccgaaaga aatgattctt ctttaatcct agaaagcgaa
     5821 atagaaaaca agaaaaaaac caacaaaaaa ttacacaaat ttggaaagaa aataaagaaa
     5881 tatatcaaca aattaaaaat aaacaaaaaa caagaaagaa taatagtaat tgatgaagaa
     5941 ttaaaaatat aataataatg ttatataaat taaatatatt ataattttat cgaaagaatt
     6001 ataatataga aactcgaagc atcaatgcca aaaatataca atattaaaaa cttatgataa
     6061 taattaatta gtaaattaaa cagtagtgat aattaataat aatgtcatat taaaaaaaat
     6121 aataatatac acataaacaa aattaatgta tacatttgtt ttgtttatat ataattatta
     6181 ttactgttgt aaattagaaa aaaaaaaaat taaaaaatat ataaaataat aataataata
     6241 ataataataa taataataat aataataat
//
